臨床化学
Online ISSN : 2187-4077
Print ISSN : 0370-5633
ISSN-L : 0370-5633
慢性関節リユウマチにおける関節液, 血清中のSuperoxide Dismutase活性値, 過酸化脂質値, セルロプラスミン値の検討
徳永 賢治土居 修宍野 宏治村瀬 光春武内 望篠原 力雄石黒 伊三雄
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1989 年 18 巻 2 号 p. 42-48

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The levels of superoxide dismutase (SOD), lipid peroxide (LPO) and ceruloplasmin in sera and synovial fluids were determined in rheumatid arthritis (RA), osteoarthritis (OA) and infectious arthritis (IA),
Total SOD, Cu, Zn-SOD activity and LPO level in synovial fluid from patients with RA and IA were found to be remakably higher than from OA, hower, Mn-SOD activity showed no difference.
The SOD activity in serum from RA was singnificantly lower than OA, but the LPO value Showed no difference.
Ceruloplasmin levels were increased in serum and synovial fluid from RA.
These results suggest that synovial fluid measurment may be useful in clinical evaluation of chronic inflammatory disorders.
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