Equilibrium Research
Online ISSN : 1882-577X
Print ISSN : 0385-5716
ISSN-L : 0385-5716
総説
マウス内耳への薬剤・遺伝子導入,およびホールマウント標本作製のための側頭骨解剖・手技
吉村 豪兼小口 亜莉沙工 穣
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2024 年 83 巻 6 号 p. 473-478

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The mouse has been a practical animal model for studying the inner ear. Understanding the anatomy of the murine inner ear is essential when delivering drugs or vectors for therapeutic studies. In addition, a knowledge of dissection techniques is necessary for performing immunohistological examinations of the cochlea and vestibule. However, there have been few comprehensive reports describing these techniques to date. In this paper, I summarize the anatomical knowledge and methods for whole-mount dissection of the murine inner ear, providing a practical guide to advance our understanding of the inner ear physiology and pathology using mouse models.

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