A beef cattle liver and swine liver were collected between July to November 2013 in Japan. Campylobacter jejuni and C. coli were isolated from 21.6% (109/505) of beef cattle liver and from 14.8% (74/500) of swine liver. A total of 184 Campylobacter isolates (109 beef cattle liver isolates and 75 swine liver isolates) were subjected to antimicrobial resistance profiling against eight different antimicrobials. Regarding antimicrobial resistance, C. jejuni (beef cattle liver isolates) and C. coli (swine liver isolates) showed resistance against 1 to 5 and 1 to 6 antimicrobial agent, respectively. For C. jejuni isolates, antimicrobial resistance rates were observed in 2.0% of EM and CP to 58.6% of TC. And for C. coli isolates, these were observed in 8.3% of CP to 84.7% of TC. Pulsed-field gel electrophoresis (PFGE) patterns were examined in Ciprofloxacin (CPFX) resistant strains. CPFX resistant C. jejuni and C. coli were classified into 17 different PFGE patterns and 19 patterns, respectively.