炎症・再生
Online ISSN : 1880-5795
Print ISSN : 1346-8022
ISSN-L : 1346-8022
Review Article
完全長cDNA とゲノム医科学
菅野 純夫
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ジャーナル フリー

2003 年 23 巻 3 号 p. 157-163

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抄録
As the result of the human genome project, the entire sequence of human genome was determined. Unfortunately, it is still not a trivial task to identify genes from these genome sequences only by the computational methods. Thus, full-length cDNAs are indispensable for the identification of genes and the determination of their structures. In addition, cDNAs will be a valuable resource for the functional analysis of the gene. We have performed so called FLJ project of collecting and determining the entire sequences of putative full-length cDNA clones. In this project, we extensively used cDNA libraries made by oligo-capping method. In this review, I will describe the current status of FLJ project and high-through-put functional analysis using full-length cDNA clones obtained by FLJ project.
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© 2003 日本炎症・再生医学会
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