This study was performed on the possibility of clinical application of Percutaneous Transluminal Coronary Laser ANGIOPLASTY(PTLCA) by“Hot-Tip”lasing. The Nd-YAG laser fiber (metal coating special fiber) with the builtin guide wire. This special fiber was connected with Fine-Ceramics tip. The first, Nd-YAG laser through this fiber was irradiated to the postmortem human coronary arteries. The second, the PTLCA by Seldinger method was tried to dogs and 2% cholesterol feeded pigs in vivo.
From the above experiments, the amounts of adequate Laser energy for one time laser irradiation was decided 5 to 7 joules. Through this procedure, complication, that is, perforation of vessel or vasospasms,et al. were not recognized at all. So, it is considered that this PTLCA system will have possibility of clinical application.
