抄録
The change of tissue temperature on rat brain tumor during HpD-PDT was studied. An increasing of the temperature was dependent on the dose rate of the laser. That is, at the tip of an optical fiber inserted into rat brain tumor, the temperatures increased from 36.0°C to 42.0, 47.8 and 54.7°C when 100, 200, and 300mW laser light were delireved respectively. At the point of 5mm away from the tip, the temperatures increased from 36.0°C to 38.5, 41.0 and 41.5°C. A possibility of hyperthermal effect during HpD-PDT was suggested when the power of laser exceeded 300 mW/cm2.
