Exploring Optimal Conditions for Brain Mapping with Transcranial Magnetic Stimulation

抄録

Transcranial magnetic stimulation (TMS) is a neurostimulation technique that can be used to identify cortical functional sites in the investigation of brain functions and holds clinical significance for pre-surgical mapping of motor and language functions. Although various motor brain mapping methods have been explored, the extensive number of TMS stimuli presents a burden on patients, limiting its application. The aim is to explore the optimal stimulus conditions necessary for effective TMS mapping. In particular, this study investigates the impact of changing the TMS coil parameters (orientation and position) on the estimation of cortical sites based on the relationship correlation between computed TMS-induced electric currents in the brain and measured MEPs. It is expected that is that refining the parameters will facilitate more detailed and practical mapping.