This study focuses on the fundamental characteristics of DME combustion, aiming at the development of a new low-NOx combustion technology suitable to DME. Combustion experiments using diffusion burner were conducted for characterizing DME through the comparison with the results of LPG and ISA-city gas. The NOx emission of the DME was over 130ppm, which is higher than that by the other fuels. By applying the low-NOx combustion system, referred to the tube-nested combustion, NOx emission of DME was extremely reduced from 120ppm to 20ppm at 0% O_2. Then the dimension of the burner plate was examined to optimize the DME combustion.