Abstract
The present report describes experiments designed to derive the effect of tangle on the blood pressure and urinary excretion of sodium in rats.
Basal diet was consisted of mostly milled washed rice, solvent extracted soybean, thiamine and vitamin A.
The diet was made high salt diet by inclusion of 2.5g sodium chloride per 100g of diet. Powdered tangle, its ignited residue, its water extractive matter or extracted residue were included in the basal diet. Four feeding experiments were conducted in all. In every case the lower blood pressure was observed in rats fed with tangle supplemented diet than in those fed the basal diet, while the water extractive matter and the ash of tangle has little effect if any on the blood pressure.
The excretion of urinary sodium has increased in rats fed the diet after the addition of tangle or water extracted residue to the basal diet.
Since the amount of riboflavin and pantothenic acid was found to increase in liver, kidneys and feces of rats fed tangle or water extracted residue, present authors speculated the increased supply of riboflavin and pantothenic acid by the intestinal synthesis may favour the excretion of urinary sodium and prevent the elevation of blood pressure induced by high salt diet.
Koyanagi et al. have reported the increased excretion of sodium in urine and prevention of high blood pressure by supplementing riboflavin and pantothenic acid to the high salt diet consisting of rice and defatted soybean flour12) 13).
