A large quantity of chemical waste is created daily from the laboratories of schools at all levels, while chemistry teachers are emphasizing the importance of pollution free manufacturing systems and saving natural resources in their classes. Development of an environmentally benign teaching method is, therefore, an important current topic in the field of chemical education. The author has reported that chemical experiments using a microscope are advantageous for a variety of reasons other than traditional teaching methods. In this paper, eight types of chemical experiments using a microscope were demonstrated at a high school from the standpoint of "green chemistry"; the total amount of chemical waste in each experiment was calculated and compared with that generated by the respective traditional teaching method. It was confirmed that the methodology using a microscope in chemical experiments makes it possible to drastically reduce chemical waste.