抄録
Object: We analyzed relations between stroke and hyper tension or the therapy with resent elder Japanese data.
Methods: 1) We performed a case control study by comparing rates of hypertension or the therapy with the data of patients in JSSRS and a general population. 2) We performed a open cohort study to analyze a relation between blood pressure revel and total mortality with a general population. The analysis repeated in each gender and each generation (40-59 years, 60-69 years, 70-79 years, 80-89 years). 3) We performed a open cohort study to calculate the risks of hypertension therapy in the same blood pressure revels with another general population.
Results: Hyper tension showed significant risk to cerebral infarction in people less than 60 years old, but did not in people more than 60 years old. Hyper tension therapy showed significant risk to cerebral infarction in all generation. Blood pressure showed did not show significant risk to total mortality until 160/100 (systolic/diastolic) in both gender and all generations of the general population. Hyper tension therapy showed significant risk to total mortality at the revel of blood pressure over 180/110. The reason is assumed as the patients with higher blood pressure were treated with hard therapy.
Discussion: Hypertension therapy is aiming to decrease blood pressure less than 140/90 now. This study shows the goal is not adequate for elder people. Cerebral infarction may result from the hard treatment.
