4. Calcitonin gene-related peptide遺伝子の脳底動脈への導入はくも膜下出血後の血管攣縮を予防する

抄録

Gene transfer to cerebral arteries is an appealing strategy to modulate vascular function, and an possible technique for treatment of verebrovascular diseases. We have recently reported that gene transfer of calcitonin gene-related peptide in vivo to rabbits prevented constriction of the basilar artery in vivo after experimental subarachnoid hemorrhage, both when the vius was applied before and after hemorrhage. Here, we demonstrate results of this study, and discuss the possibility of gene therapy for stroke.