医療情報データを用いた医薬品安全性評価とその小動物医療への応用可能性

抄録

Parmacoepidemiological studies that use medical information databases are powerful tools for post-marketing drug safety assessment. Recently, some medical information databases including claims data and electronic medical records data have become available in Japan. To conduct optimum drug safety assessment, researchers should comprehend the strengths and limitations of such databases. This paper deals with two important methodological topics in the field of pharmacoepidemiological ; causal inference and self-controlled methods. Also, pharmacoepidemiological studies may be important to find out rare serious adverse events of drugs, although few studies have focused on drug safety assessment in small animal medicine.