2008 Volume 61 Issue 5 Pages 367-371
Experiments were conducted to investigate whether pigs could be infected with bovine viral diarrhea virus (BVDV) by transfer into a BVDV-contaminated environment. Pigs in test groups 1 and 2 were transferred intoa pigsty in which culture medium supernatant from cells used to propagate wild-type BVDV and urine from persistentlyinfected calves were scattered over the floor and chow. Test group 2 also received an oral BVDV gavage.A positive control group received a BVDV solution through intramuscular inoculation. A negative controlgroup was kept in a pigsty in which a culture medium that did not contain BVDV was dispersed. For pigsin test groups 1 and 2 and the positive control group, BVDV was isolated from sera on days 3 to 14 and an elevated BVDV neutralizing antibody was measured starting on day 14. The data shows that a BVDV-contaminatedenvironment can be a source of BVDV infection for pigs.