Age-Related Changes in Calretinin-Immunoreactive Periglomerular Cells in the Rat Main Olfactory Bulb

In Koo HWANG; Ki-Yeon YOO; Young Sam NAM; Jung Hoon CHOI; Kangmoon SEO; In Se LEE; Ju Young JUNG; Tae-Cheon KANG; Yang-Seok OH; Moo Ho WON

doi:10.1292/jvms.68.465

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Age-Related Changes in Calretinin-Immunoreactive Periglomerular Cells in the Rat Main Olfactory Bulb

In Koo HWANG, Ki-Yeon YOO, Young Sam NAM, Jung Hoon CHOI, Kangmoon SEO, In Se LEE, Ju Young JUNG, Tae-Cheon KANG, Yang-Seok OH, Moo Ho WON

Author information

In Koo HWANG
Department of Anatomy, College of Medicine, Hallym University
Ki-Yeon YOO
Department of Anatomy, College of Medicine, Hallym University
Young Sam NAM
Departments of Anatomy, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University
Jung Hoon CHOI
Departments of Anatomy, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University
Kangmoon SEO
Department of Veterinary Surgery, College of Veterinary Medicine, Seoul National University
In Se LEE
Departments of Anatomy, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University
Ju Young JUNG
Department of Anatomy, College of Medicine, Hallym University
Tae-Cheon KANG
Departments of Anatomy, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University
Yang-Seok OH
Department of Medical Genetics and Experimental Animal Center, College of Medicine, Hallym University
Moo Ho WON
Department of Anatomy, College of Medicine, Hallym University

Keywords: aging, calretinin, degeneration, periglomerular cells, SD rat

JOURNAL FREE ACCESS

2006 Volume 68 Issue 5 Pages 465-469

DOI https://doi.org/10.1292/jvms.68.465

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Abstract

The changes of calretinin (CR)-immunoreactive periglomerular cells in the glomerular layer of the main olfactory bulb (MOB) were investigated in rats differing ages from postnatal month 1 (PM 1) to PM 24. The number of cresyl violet-positive periglomerular cells was similar between PM 1 and PM 12, but they decreased slightly in the PM 24 group. The size of CR-immunoreactive periglomerular cells in the glomerular layer increased with age, while their numbers did not change significantly in the PM 6-PM 24 groups. In the PM 24 group, numbers of CR-positive periglomerular cell bodies and their processes decreased, while the size of CR-positive cell bodies in the glomeruli was larger than that of the previous groups. These results suggest that CR-immunoreactive periglomerular cells in the rat MOB are well-developed in the PM 6 group, and that periglomerular cells in the PM 24 group show poor CR-immunoreactivity compared to those in the PM 6 group.

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