Journal of Veterinary Medical Science
Online ISSN : 1347-7439
Print ISSN : 0916-7250
Internal Medicine
Effects of D-allulose on glucose metabolism after the administration of sugar or food in healthy dogs
Naohito NISHIIToru NOMIZOSatoshi TAKASHIMATatsuya MATSUBARAMasaaki TOKUDAHitoshi KITAGAWA
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キーワード: D-allulose, dog, glucose, insulin, rare sugar
ジャーナル フリー

2016 年 78 巻 11 号 p. 1657-1662

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D-allulose is a C-3 epimer of D-fructose and has recently been investigated for its hypoglycemic effects. In the present study, the effects of D-allulose on glucose metabolism were evaluated in healthy dogs administrated sugar or food. The oral administrations of D-allulose decreased plasma glucose concentrations after oral glucose or maltose administration, with a diminished plasma insulin rise. The glucose suppressive effect of D-allulose was also observed after intravenous glucose administrations without increase in plasma insulin concentration. In contrast, D-allulose showed no effect on plasma glucose and insulin concentrations after feeding. The present results suggest that D-allulose administration may be beneficial in dogs with impaired glucose tolerance. Further studies investigating the therapeutic efficacy of D-allulose in diabetic dogs are required.

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