Evaluation of chlorine dioxide in liquid state and in gaseous state as          virucidal agent against avian influenza virus and infectious bronchitis          virus

Chisaki KADOTA; Yu MIYAOKA; Md Humayun KABIR; Hakimullah HAKIM; Md Amirul HASAN; Dany SHOHAM; Harumi MURAKAMI; Kazuaki TAKEHARA

doi:10.1292/jvms.23-0194

Avian Pathology

Evaluation of chlorine dioxide in liquid state and in gaseous state as virucidal agent against avian influenza virus and infectious bronchitis virus

Chisaki KADOTA, Yu MIYAOKA, Md Humayun KABIR, Hakimullah HAKIM, Md Amirul HASAN, Dany SHOHAM, Harumi MURAKAMI, Kazuaki TAKEHARA

著者情報

Chisaki KADOTA
Laboratory of Animal Health, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan
Yu MIYAOKA
Laboratory of Animal Health, Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan
Md Humayun KABIR
Laboratory of Animal Health, Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan
Hakimullah HAKIM
Laboratory of Animal Health, Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan
Md Amirul HASAN
Laboratory of Animal Health, Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan
Dany SHOHAM
Begin-Sadat Center for Strategic Studies, Bar-Ilan University, Ramat Gan, Israel
Harumi MURAKAMI
Laboratory of Animal Health, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan
Laboratory of Animal Health, Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan
Kazuaki TAKEHARA
Laboratory of Animal Health, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan
Laboratory of Animal Health, Cooperative Division of Veterinary Sciences, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan

キーワード: aerosol disinfection, avian infectious bronchitis virus, avian influenza virus, chlorine dioxide, virucidal agent

ジャーナルオープンアクセス

2023 年 85 巻 10 号 p. 1040-1046

DOI https://doi.org/10.1292/jvms.23-0194

Browse “Advance online publication” version

詳細

抄録

The antiviral activity of chlorine dioxide (ClO₂) in liquid (ClO₂ gas dissolved liquid) and gaseous state against avian influenza virus (AIV) and infectious bronchitis virus (IBV) was evaluated. To evaluate the effect of ClO₂ in liquid state, suspension tests (10 ppm) and carrier tests in dropping / wiping techniques (100 ppm) were performed. In the suspension test, virus titers were reduced below the detection limit within 15 sec after treatment, in spite of the presence of an accompanying organic matter. In the carrier test by dropping technique, AIV and IBV were reduced to below the detection limit in 1 and 3 min, respectively. Following wiping technique, no virus was detected in the wiping sheets after 30 sec of reaction. Both viruses adhering to the carriers were also reduced by 3 logs, thereby indicating that they were effectively inactivated. In addition, the effect of ClO₂ gas against IBV in aerosols was evaluated. After the exposure of sprayed IBV to ClO₂ gas for a few seconds, 94.2% reduction of the virus titer was observed, as compared to the pre-treatment control. Altogether, hence, ClO₂ has an evident potential to be an effective disinfectant for the prevention and control of AIV and IBV infections on poultry farms.

責任著者(Corresponding author)

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