Journal of Veterinary Medical Science
Online ISSN : 1347-7439
Print ISSN : 0916-7250
ISSN-L : 0916-7250
Effect of Maternal Paraquat Administration on the Fetal Ductus Arteriosus in the Rat
Mitsuyuki SHIRAIKazuyoshi ARISHIMAToshio MASAOKAHirotaka TAKAGIMasako YAMAMOTOYasunobu EGUCHIFumiaki AKAHORI
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1994 Volume 56 Issue 2 Pages 413-414

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Abstract
The ductus arteriosus (DA) in the fetal rat was calibrated using a whole-body freezing method, 3 hr after maternal treatment with paraquat at a dose of 25 mg/kg of body weight on days 19-21 of gestation. On days 20 and 21, the DA was significantly constricted. The DA was also significantly constricted on day 19 2/3 but not on day 19 1/2. It is concluded that paraquat has a constrictive effect on the DA and that the onset of this effect occurs in the first half of day 19 of gestation.
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© The Japanese Society of Veterinary Science
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