沖縄における健康学童の咽頭溶連菌と血清抗体価に関する研究

抄録

The importance of group A hemolytic streplococci in the etiology of rheumatic fever and acute nephritis has been well documented. Further, there are many reports on the epidemiological significance of antistreptolysin-O titer and antistreptokinase titer as related to streptococcal infection, rheumatic fever, and acute nephritis. Therefore the studies on rheumatic fever and acute neptritis should be based on epidemiology of streptococcal infection.
In order to study the change in the type distribution which accurred after the return of Okinawa to Japan in May, 1972, throat culturing for beta hemolytic streptococci was carried out annually among school children in Okinawa since March, 1971. The isolated strains of group A hemolytic streptococci were then examined serologically by T-agglutination method.
Moreover, the distributions of antistreptolysin-O titer and antistreptokinase ti ter in Okinawa were examined in 1973.
The conclusions of this research are as follows:
1) The incidence of beta hemolytic streptococci among school children has been higher in all regions of Okinawa than in any of the other regions of Japan.
2) T-12 was as dominant in Koza city as in Tokyo.
3) The predominant types were different among the Miy ako islands.
4) In Hateruma island, the dominant type has changed from T-11 to T-28, after the return of Okinawa to Japan.
5) T-14 was isolated from every region of Okinawa as one of the predominant types.
6) Although the isolation rate of beta hemolytic streptococci has been high in Okinawa, the mode of the antistreptolysin-O titer distribution and also antistreptokinase titer distribution was considerably low.