抄録
A 25-year-old female case developed severe toxicoderma associated with liver damage after receiving acetylsalicylic acid, sulpyrin and chloramphenicol for upper respiratory infection. Despite treatment with glycylrrhizin, reduced glutathione, ascorbic acid and betamethasone as well as drip infusion of fluids for 11 days, her skin symptoms did not improve and the liver damage was aug-mented. Following administration of large doses of vitamin E (800-1000mg/day) and topical application of vitamin E ointment for 3 weeks, her skin symptoms disappeared completely and 11 weeks after the therapy findings of the liver function tests returned to almost normal.
