抄録
In order ao elucidate the effects of cinchophen on hypothalamic electrical activity, conscious dogs were used in this experiments.
Intravenous administration of sodium cinchophen in a dose of 200mg/kg body weight caused hyperglycemia and evoked seizure discharge in record of the middle hypothalamus. Glucose also causes excitation of middle hypothalamic electrical activity similar to that induaed by cinchophen.
These findings strongly suggest that cinchophen acts through hyperglycemia directly upon the middle hypothalamus.