抄録
Background and Aims : We investigated histopathological differences between granuloma pyogenicum (GP), intradermal (IGP) and subcutaneous (SGP) granuloma pyogenicum. Methods : Twenty cases of GP, one case of IGP and one case of SGP were immunohistochemically studied for the expression of CD34 and Factor VIII-related antigen (F VIII-RA). Results : Immunohistochemistry for CD34 demonstrated various staining patterns in GP, IGP and SGP. F VIII-RA was expressed immunohistochemically in GP, but staining was completely absent in IPG and SPG. Conclusions : These results suggested that immunohistochemical difference among these tumors might reflect the degree of maturation in neoplastic endothelial cells.
