Abstract
We carried out a role of horny layer of skin as for skin contamination. In the case of the skin with horny layer, the internal permeance of 131I-Na was slow and slight. In the case of the skin without horny layer, we had better think that the internal permeance of 131I-Na was rapidly and revealed the internal contamination as almost same as in the case of venous injection of 131I-Na. For the prevention of the internal contamination, it was necessary that horny layer of skin was intact. In the case of the normal skin with horny layer, the permeance of 131I-Na was slow by 20 min. after application and then the contamination of 131I-Na should be removed within 20 min. after application. Out of the radioactive substances, iodine, anion, has the easy permeability and volatility. So we have pay expressly attention to handling it comparing with the other radioactive substances.
