短期記憶および作業記憶の評価系の確立

抄録

Memory can be classified into at least short-term memory and long-term memory based on its retention time. Short-term memory usually disappears immediately, but when some event, gaze or novelty happens at the same time, it is selectively converted to long-term memory. Work memory is given as a very short memory retention, but this is used as temporary memory retention. In this research, we have established a fundamental research and evaluation system for short-term memory and work memory using spatial object recognition task and modified T-maze. These tests will be used to quantify cognitive deficits in transgenic strains of mice and evaluate novel chemical entities for their effects on cognition.