整形外科と災害外科
Online ISSN : 1349-4333
Print ISSN : 0037-1033
ISSN-L : 0037-1033
長期透析後に股関節に発症したアミロイド性骨関節症の1症例
加来 信広高下 光弘片岡 晶志松本 博文荻本 普作津村 弘
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2001 年 50 巻 1 号 p. 249-254

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A forty-five-year-old female who had been on hemodialysis for twenty six years developed extensive bone cyst in the femoral head. The cystic lesion showed low-signal intensity on T1-weighted images of magnetic resonance imaging. On T2-weighted images, it showed iso-signal intensity. She experienced hip pain and the cystic area in the plain radiograph covered 37.5% of the femoral head using the lateral head index. We therefore performed hip arthroplasty with bipolar endoprosthesis. At operation, we found a change in the color of the articular cartilage, synovium proliferation and granulation tissue in the joint space. Histological examination using dylon staining showed amiloid deposition in the cartilage, synovial membrane, granulation tissue and bone specimens. In addition, the existance of many inflammatory cells in the synovial membrane and some giant cells like osteoclast contacting with the bone trabecular around amiloid was demonstrated pathologically.
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