Clivus Metastasis From Gastric Signet Ring Cell Carcinoma After a 10-Year Disease-Free Interval —Case Report—

Masamichi FUKUSHIMA; Yoichi KATAYAMA; Yutaka SHIGEMORI; Hiroshi MIYAKE; Teruyasu HIRAYAMA; Akio KOTANI

doi:10.2176/nmc.52.751

Case Reports

Clivus Metastasis From Gastric Signet Ring Cell Carcinoma After a 10-Year Disease-Free Interval

—Case Report—

Masamichi FUKUSHIMA, Yoichi KATAYAMA, Yutaka SHIGEMORI, Hiroshi MIYAKE, Teruyasu HIRAYAMA, Akio KOTANI

著者情報

キーワード: clivus metastasis, signet ring cell carcinoma, abducens nerve palsy, late recurrence, tumor dormancy

ジャーナルオープンアクセス

2012 年 52 巻 10 号 p. 751-753

DOI https://doi.org/10.2176/nmc.52.751

詳細

抄録

A 64-year-old male presented with an extremely unusual case of solitary clivus metastasis from gastric cancer manifesting as mild headache and diplopia 10 years after radical excision of the primary tumor. The patient underwent surgical resection using an endoscopic transsphenoidal approach. Histological examination revealed typical signet ring cell carcinoma (SRC) which was identical to that of the previous gastric cancer. Why the late recurrence occurred such a long time after the first surgery and how it spread to the clivus remain unclear. The characteristics of SRC and the process of “tumor dormancy” may have been involved in the mechanism underlying late metastasis.

責任著者(Corresponding author)

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