Abstract
We investigated the effects of different isoflavone aglycone ratios in lactic acid-fermented soymilk on hepatic lipid metabolism in rats fed a high fat and high cholesterol diet. Male Sprague-Dawley rats (7 weeks old) were fed a control diet (AIN-93G), high fat and high cholesterol diet, or high fat and high cholesterol diet containing fermented soymilk with a low isoflavone aglycone ratio or fermented soymilk with a high isoflavone aglycone ratio for 5 weeks. Both lactic acid-fermented soymilks exhibited lipid metabolism-modulating function, and the function was stronger in fermented soymilk with a high isoflavone aglycone ratio than in that with a low isoflavone aglycone ratio. It was proposed that isoflavone aglycones stimulated the lipid metabolism-modulation effects in liver.
