Abstract
The effects of non-dialyzable extracts of some edible plants on the inhibition of melanogenesis of B 16 mouse melanoma cells, the immunoglobulin secretion of HB 4 C 5 human-human hybridoma cells, and the differentiation of U-937 human myeloid leukemia cells were examined. The non-dialyz-able extracts of green tea, eggplant, kiwi fruit, carrot and spinach inhibited melanogenesis of B 16 cells. The highest activity on inhibition of melanogenesis was shown by the non-dialyzable extract of green tea, and the extract decreased melanin production by 46% compared with the control. The IgM secretion of HB 4 C 5 cells was promoted by the non-dialyzable extracts of green tea. The processed spinach extract induced the adhesion and morphological change of U-937 on the culture plate, and the expression of cell surface antigens of CD 11 b of U-937 cells was also induced by this extract.
