Abstract
The effect of gelatin and collagen peptides (each 50 and 100mg oral administration for 21 days) on the skin collagen synthesis, which used the index of hydroxyproline content in the soluble fraction of skin, was studied by male Wistar rats. In the case of unshaved or shaved treatment, the hydroxyproline contents in 50 and 100mg gelatin groups did not increase compared with control group. In contrast, the hydroxyproline contents in 50 and 100mg collagen peptides groups resulted in a significant increase compared with control group. These results suggest that the administration of collagen peptides enhance the hydroxyproline content in the soluble fraction of skin, which may be related to skin collagen synthesis of rats, more easily than gelatin.
