Abstract
Eleven male mice of 90 days of age were injected daily with 10 mg of vitamin E (“Juvela” prepared by Eisai Co., Ltd. ). After 40 days, they were sacrificed and their testes were histologically examined.
1) In the seminiferous tubules, the germinal cells except spermatids and sperms did not indicate a marked histological change in number and cytological appearence, and marked stimulation of division in the germinal cells was not observed, but mature spermatids and sperms increased generally by administration of vitamin E.
2 ) Concerning the interstitial cells, it was observed that hypertrophy and an appearence of vacuoles in the cytoplasm were somewhat more frequently found than in the control.
3) These data suggest that vitamin E administration activates spermiogenesis and function of interstitial cells in mature mice.
The authors wish to express their gratitude for constant guidance and helpful suggestions to Prof. Dr. K. Yamada and for help of Assist. Prof. Dr. M. S a n o. The authors are also indebted to Mr. F. Sanda in preparing the microphotographs in this article.
