The authors report a case of submandibular cancer that showed unusually high CEA level, 7380-11500mg/ml, as measured by a Roche's kit.
The extremely high level which could not be found even in literature might have been caused either by depressive action upon the reappearance of CEA due to the changes of the herediatary factors wrought by the cancer or increased excretion of CEA into the peripheral blood due to extensive systemic metastases of malignant cells with distorted hereditary factors.
Taking into consideration the results of measurements of lymphocytes subpopulation, which was used as an immunological parameter, skin tests with PHA and PPD, and serum immunoglobulin levels, the authors could not rule out the presence of some relation between the CEA level and immunogenic function.
