Eight cases diagnosed with human intestinal spirochetosis (HIS) from January 2019 to July 2019 in our hospital were compared. The patients were 7 males and 1 female; their ages ranged from 17 to 72 (mean 52.8) years. Five out of the 8 patients had symptoms. Colonoscopic findings included redness (n=4), edema (n=2), and polyps (n=4). These eight patients comprised 2.1% of all patients who underwent colonoscopy and histological examination during the same period. Metronidazole was administered to two patients, one of whom showed improved symptoms. Currently, the diagnosis of HIS largely depends on pathological examination. HIS should be considered as a cause of gastrointestinal symptoms of unknown etiology, and we believe that eradication may be an option for treatment.
