著明な蛋白漏出をきたした薬剤起因性急性胃粘膜病変の1例

抄録

A 19-year-old male was admitted to our hospital with chief complaints of epigastralgia and systemic edema. They occured 2 days after taking a non-steroidal anti-inflammatory drug. Serum total protein was 3.1g/dl.
Endoscopic examination revealed an acute gastric mucosal lesion (AGML) at the area from the middle body to the antrum of the stomach. α₁-anti-trypsin gastric clearance markedly increased, indicating that he had a protein-losing gastroenteropathy. He was treated with H₂-receptor antagonist for 4 weeks and relieved from the systemic edema.