A 74-year-old female underwent gastrointestinal endoscopy due to chief complaint of nausea. Endoscopy revealed gastric polyp with stalk below the esophagogastric junction. It had the erosion and the bleeding on the surface of the top. Polypectomy was done due to the suspicious for malignancy through the biopsy. However, the tissue, which was suspected for malignancy was a part of pseudosarcomatous granulation tissue, and the polyp as a whole was the hyperplastic polyp with the erosion of the top.
Pseudosarcomatous change is sometimes found in the inflammatory reaction, especially the reparative process of the erosion. However, it is said that the ease is very rare.
Histologically, its change consists of the granulation tissue with giantic and atypical histiocytes, therefore, some cases were misdiagnosed for malignancy in small biopsies.
Our experience suggests that it is not difficult to deny malignancy, if you examine the polypectomized material, and compair it with a histological features of granulation tissue in a biopsy.
