The patient is a 61-year-old-man who complained of headache and diziness. Brain CT showed homogenous enhanced mass lesions in the left frontal lobe and right occipital lobe. In the operation, brain tumor was diagnosed metastatic malignant melanoma originated on the left heel. Endoscopic finding showed Borrmann type 2-like lesion in the second portion of the duodenum. Histological finding of biopsy specimen revealed metastatic duodenal malignant melanoma.●改行● The patient was treated with ACNU and VCR after the resection of the original cancerous lesion. Follow-up endoscopic examination, performed 8 weeks after chemotherapy, revealed the features like ulcer scar lesion and histological diagnosis was group II. We reported a rare case of metastatic duodenal malignant melanoma with remarkable response to anti-cancer chemotherapy.
