A polypoid lesion (11×12mm) was found in the second portion of the duodenum in an otherwise healthy 61-year-old male by upper GI endoscopy. The histopathological examination on biopsy specimen revealed group III atypia. Subsequently, endoscopic polypectomy was performed and the histopathological examination on the resected specimen revealed tubulopapillar adenocarcinoma embedded in tubular adenoma. The carcinoma cells were found only inside the lamina propria mucosa and no invasion into blood and lymphatic vessels was detected. The resection edge was free of adenoma and adenocarcinoma cells. Following examination has shown neither local recurrence of neoplasm nor metastatic events.
