食道静脈瘤に対する内視鏡的結紮療法と硬化療法併用例の治療成績

抄録

We analyzed the effects of combination therapy for esophageal varices, endoscopic variceal ligation (EVL) and endoscopic injection sclerotherapy (EIS) . Subjects were 7 cases treated by the combination therapy. And compared subjects which were treated by EVL only were 27 cases. All cases were positive of red color (RC) sign and therapeutic goal were negative of RC sign. Effective cases were negative of RC sign at one month after those treatments.
Seven cases (100%) were effective after the combination therapy and 21 cases (77.8%) were after EVL only. As for the treated form of varices, 7 cases (100%) were F₁ or F₀ after combination therapy, but 14 cases (66.7%) were after EVL only. The relapse rate of these effective cases after combination therapy was 20.0% at 6 months, and after EVL only was 29.9% at 6 months, 56.2% at 12 months.
These results suggest that combination therapy have no significant statistical difference in relation to efficacy and relapse rate at 6 months. But we consider that the combination therapy is more eradicated therapy than EVL only and further study is necessary for comparing the relapse rate. And we think that intravariceal EIS is effective to eradicate gastric varices.