We evaluated 13C-urea breath test (UBT) in a diagnosis of Helicobacter pylori (HP) after treatment with lansoprazole and clarithromycin (CAM) or amoxicillin (AMPC) . Seventy three patients inclused 35 gastric ulcer, 15 duodenal ulcer and 73 chronic gastritis, treated for 14 days with 30mg of lansoprazole, 600mg of CAM or 2000mg of AMPC in a day. Antral, lower body and upper body biopsy samples were taken for culture and histology. We evaluated 73 chronic gastritis with Sydney classification.
Eradication was defined as the absence of HP in all speciments. HP was eradicated by treatment in 63.0% (46/73) , by CAM/lansoprazole in 84.3% (16/19) and by AMPC/lansoprazole in 55.5% (30/54) . Severity of the side effects did not occurred. It was valid that AMPC/lansoprazole were eradicated rather than CAM/lansoprazole. Eradication of HP with lansoprazole and CAM or AMPC provided a safe and effective, and 13C-UBT examination were useful in observing the eradication of HP.
