We evaluated 13C-urea breath test (UBT) in a diagnosis of Helicobacter pylori (HP) after treatment with lansoprazole and clarithromycin. Fifty four patients inclused 24 peptic ulcer and 54 chronic gastritis, treated for 14 days with 30mg of lansoprazole and 600mg of clarithromycin in a day. Antral, lower body and upper body biopsy samples were taken for culture and histology. We evaluated 54 chronic gastritis with Sydney classification.
Eradication was defined as the absence of HP in all speciments. HP was eradicated by treatment in 55.5% (30/54) . Severity of the side effects did not occurred. It was possible that low grade erosive gastritis were eradicated rather than severe grade erosive gastritis. Eradication of HP with lansoprazole and clarithromycin provided a safe and effective, and 13C-UBT examination were useful in observing the eradication of HP.
