1996 年 49 巻 p. 204-205
A 54-years-old female visited our hospital for bloody stool. She had a history of having taken diclofenac soudium as suppositories 10 days and tablet for 3 days for her lumbago.
Colonoscopic finding showed multiple aphthoid ulcers accompanied with the edema and redness in the terminal ileum and revealed some small ulcers in the transverse colon. Another colonic mucosa showed normal vascular pattern and no inflammatory findings. Microscopic view of the biopsy specimen obtained from the margin of ulcer in the terminal ileum revealed erosin and slight infiltration of lymphocyte.
We diagnosed NSAIDs induced enterocolitis, and we ordered her to stop taking NSAIDs. After two weeks, the ulcers in the terminal ileum became healed colonoscopically. This kind of case were rare and the literatures regarding the similar cases were also reviewed.