カンボジア王国, 村落地域住民における歯周炎レベルと心疾患の相関について

抄録

As members of the Organization of International Support for Dental Education (OISDE) , we had been implementing“the project of primary health care and prevention of systemic damages caused by peri-odontal infection at the rural area in the Kingdom of Cambodia”. This project was supported by Japan International Cooperation Agency (JICA) since March 2004 until March 2005. The targeted areas were composed of 7 provinces and 25 districts. The subjects were 1,296 residents. As one of the risk factors, living environment risk (LE) factor was charted based on a five-grade method according to our original classification. Systemic medical condition of the residents was charted by interview method into history of systemic diseases and history of tropical infections. The dental intelligence quotient (dental IQ) concerning periodontal infection was charted by question and answer method according to a five-grade classification. As part of behavioral risk factor for periodontal inflammation, the number of frequency of brushing the teeth was evaluated using interview method. The level of periodontitis was evaluated by periodontal probing using the four-point method and bleeding on probing (BOP) for all remaining tooth/teeth in each resident. The medical examination, which includes heart murmurs, lung sounds, blood pressure, urine test, and electrocardiogram (ECG) , was investigated by a physician. In the result, 29% of the residents were discovered with abnormal heart murmur or ECG findings. These comprised 34% mitral valve murmur, 18% tricuspid valve murmur, and 16% other abnormal heart sounds. The ECG findings in the residents with abnormal heart findings revealed 23% due to premature atrial contraction, 14% atrio-ventricular (A-V) Block, and 6% was caused by other abnormal ECG findings. The onset of heart disease was statistically different between the group with over 3.5 mm depth and the group with less than 2 mm depth when analyzed by t-test. In spite of the heart disease was detect in no BOP group of 20%, the heart disease was significantly tendency by statically analyze increasing according to over 20% of BOP. This result strongly considered that chronic periodontal inflammation has one of the caused damages to the heart valves and is influenced by bacteremia. Nihon Shishubyo Gakkai Kaishi (J Jpn Soc Periodontol) 48 : 208-217, 2006.