The behavior of homologous chromosomes during meiosis.

Ybshimka Azumi

doi:10.5685/plmorphol.18.3

減数分裂時に見られる相同染色体の挙動

安積良隆

著者情報

ジャーナルフリー

2006 年 18 巻 1 号 p. 3-12

DOI https://doi.org/10.5685/plmorphol.18.3

詳細

発行日: 2006 年受付日: - J-STAGE公開日: 2010/06/28 受理日: - 早期公開日: - 改訂日: -
訂正情報
訂正日: 2010/06/28 訂正理由: - 訂正箇所: PDFファイル訂正内容: -

訂正日: 2010/06/28 訂正理由: - 訂正箇所: キーワード情報訂正内容: Wrong : Key words: meiosis, Arabidopsis thaliana, homologous chromosome, synapsis, cycli
Right : meiosis, Arabidopsis thaliana, homologous chromosome, synapsis, cycli

訂正日: 2010/06/28 訂正理由: - 訂正箇所: 引用文献情報訂正内容: Wrong : E
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抄録

要旨:近年,シロイヌナズナ等で減数分裂期に異常が生じる挿入変異体が数多く報告されるようになり,またそれらを解析する様々な技法が確立されて,ようやく植物でも減数分裂の分子遺伝学に基づく解析が可能になってきた.当研究室でもシロイヌナズナを用いて,相同染色体の対合過程を制御するしくみを明らかにすべく,研究を行ってきた.その研究の一環として,相同染色体の対合できない変異体を単離し,その原因遺伝子の解析を行ったところ,この遺伝子,SOLO DANCERS,は減数分裂時に特異的に発現するサイクリンの遺伝子であることがわかった.このことからシロイヌナズナでは,相同染色体の対合にサイクリンが必要で,この遺伝子の変異体では相同染色体同士が全く接近しないことが明らかになった.また,FISH(fluorescent in situ hybridization)法を用いた減数分裂期の染色体の詳細な解析により,対合の開始時期にセントロメア同士が接着している様子や相同染色体分離時には染色体が末端部分で連結されている様子が観察され,セントロメアとテロメアにはこれらの時期に果す,まだ知られていない働きがあることが示唆された.

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