臨床血液
Online ISSN : 1882-0824
Print ISSN : 0485-1439
ISSN-L : 0485-1439
症例
形質細胞白血病の2症例
—細胞形態学的特徴について—
長谷川 吉康鈴木 俊光伊藤 敬大沢 仁
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ジャーナル 認証あり

1974 年 15 巻 3 号 p. 298-304

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Case 1. A 57-year-old woman, IgA plasma cell leukemia without Bence Jones proteinuria.
In this case, the nuclei of the leukemic cells exhibited indentation and lobulation similar to that seen in Rieder cells in acute myeloid leukemia. Giant plasmacytoma cells were also seen in the bone marrow smear and section. Electronmicroscopically, almost all the myloma cells showed the presence of polyribosome clusters formed by 10∼15 ribosomes, and poor developement of mitochondria and rough-surfaced endoplasmic reticulum presenting short-tubular from.
The deformity of the nuclei and the appearance of giant cells seemed to resemble to those of the reticulum cell.
Case 2. A 59-year-old man, plasma cell leukemia with λ-typed Bence Jones proteinuria.
In the electronmicroscopic observation, some of the ergastoplasmic cisternae were with the leukemic cells showed poor developement of Golgi zone, and well developed lamellar structure and others with dilated vesicular form. The cytoplasma also contained small polyribosome clusters between the nucleus and the endoplasmic reticulum.
The correlation between the presence of small polyribosome and high L chain synthesis was discussed.
著者関連情報
© 1974 一般社団法人 日本血液学会
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