A 48-year-old male was admitted to St. Lukes International Hospital, because of bleeding tendency and anemia. His peripheral blood showed pancytopenia with leukoerythroblastosis. A diagnosis of erthroleukemia was made from the finding of bone marrow, in which PAS-positive megaloblastoid cells were predominant. Chromosomal analysis of his bone marrow cells showed only abnormal cells with karyotypic instability and marked structual abnormality. He could not be induced to a remission after treatment with either DCcMP or DCcVP, instead marked neutropenia developed. Since the 49th hospital day, he displayed remittent fever and pulmonary interstitial infiltration. In spite of vigorous antibiotics treatment including sulfamethoxazole-trimethoprim, he died of respiratory failure on the 66th hospital day. Post-mortem lung specimen revealed pneumocystis carinii pneumonitis.
