1992 年 7 巻 2 号 p. 193-196
Herein presented was a 88-year-old Japanese man with one pigmented plaque-like lesion on the right temple and two on the left cheek. The temple lesion, consisted of a tumor, 2.0cm in diameter, on a plaque, 3.0×2.5cm in size. Histopathologically the plaque was senile keratosis and the tumor a type of squamous cell carcinoma which showed close contacts with infundibular parts of the residual hair follicles and showed somewhat trichilemmal-like keratinization. The smaller plaque of the left cheek, 1.7×1.4cm in size, was senile keratosis with in parts acantholytic change and early invasion. The larger one, 3.4×3.2cm in size, showed continuous changes from senile keratosis to trichilemmal carcinoma in situ, which revealed close relationship between senile keratosis and trichilemmal carcinoma (in situ) .