粉体工学会誌
Online ISSN : 1883-7239
Print ISSN : 0386-6157
ISSN-L : 0386-6157
ヒドロキシアパタイトミクロスフェアの新規合成法
飯村 健次中藤 俊明二階堂 賢佐藤根 大士鈴木 道隆
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2011 年 48 巻 3 号 p. 152-159

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A new synthesis route to hydroxyapatite microsphere was proposed. Starting from the W/O emulsion system, micron-sized precursor particles were formed autonomously. It was clarified that pH of water during hydrothermal treatment can affect the morphology of resultant hydroxyapatite particles. Particles of irregular shape could be obtained via hydrothermal treatment under ambient pH, by contrast under high-pH conditions resultant particles retain the spherical morphology of precursor particles. It was also clarified that obtained hydroxyapatite particles have negatively charged surface, which is opposite to those by general synthesis method such as precipitation. Eventually it was confirmed that lysozym which is positively charged protein can be adsorbed on the obtained hydroxyapatite particle but albumin which is negatively charged can never be adsorbed.
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© 2011 粉体工学会
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