日本口腔科学会雑誌
Online ISSN : 2185-0461
Print ISSN : 0029-0297
ISSN-L : 0029-0297
口腔悪性腫瘍に対する抗腫瘍性多糖体製剤Sizofilan併用療法の宿主免疫賦活効果
菊地 白安蒜 昌宏児野 喜穂
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1990 年 39 巻 2 号 p. 366-376

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Immunotherapy with Sizofilan has been used for treating oral cancers in our department since 1987. Eight cases were observed in this study. Immunological investigations revealed the following findings: 1) Lymphocytes decreased after operation plus radioand chemotherapy, but the return to the pretreatment level could been achieved 2-3 months after operation. 2) The values of OKT 3 and 4 well corresponded to the lymphocyte count at each stage. 3) The values of OKT 8 indicated low level in controlled cases, on the other side comparatively high level in un-controlled cases at each stage. For the reasons stated abve, Sizofilan contributes to promote active immunological mechanisms of patients concerning therapeutic procedure against cancer.
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