脂質の栄養価に関する研究-XIII

高級アルコールと脂肪酸のエステルの大量投与による白鼠のセボレヤ発生について(その2)セボレヤ症状の防止方法

抄録

In the previous paper²⁾ dealing with the seborrhea forming activity of sperm whale oil or the esters of fatty acids with higher alcohols as oleyl oleate, it was observed that the rats fed with the above lipids contained large amounts of unsaponifiable matters in viscera and muscle.
In the present study aiming at finding a preventive method of seborrhea disease, the authors obtained the following results:
(1) The rats fed with sperm whale oil were found containing in their body hydrocarbons 150 times and sterols five times as much as those in normal rats (Table 1).
(2) Experiments on various preventive methods of seborrhea have revealed that some of them are not so effective to prevent seborrhea formation as they have been believed so for a long time. However, adding of phospholipids of soy bean to the basal diets showed good effects for the prevention of seborrhea (Table 2).
(3) On the basis of these findings, when the lecithin and cephalin fraction separated from the soy bean phospholipids were compared in the preventing effect, it became clear that the latter exerts a good effect, while the former no effects, to the rats (Table 3-6).
(4) The above results are suggestive of this. As far as the present study is concerned, it is not the genuine cephalin but the crude one that shows protective effect from the seborrhea for the rats fed with sperm whale oil or oleyl oleate. Because when the cephalin fraction was prepared by treatment with solvent extraction, it was likely contaminated with some other substances.