新漁網妨汚剤, 5-Tert-butyl-2'-methyl-4'nitrosalicylanilide (MK-76) のラット

枝長 正修; 堀添 宏; 今村 博

doi:10.2331/suisan.42.371

新漁網妨汚剤, 5-Tert-butyl-2'-methyl-4'nitrosalicylanilide (MK-76) のラット

枝長正修, 堀添宏, 今村博

著者情報

ジャーナルフリー

1976 年 42 巻 3 号 p. 371-383

DOI https://doi.org/10.2331/suisan.42.371

詳細

発行日: 1976/03/25 受付日: - J-STAGE公開日: 2008/02/29 受理日: 1975/12/02 早期公開日: - 改訂日: -
訂正情報
訂正日: 2008/02/29 訂正理由: - 訂正箇所: 論文タイトル訂正内容: 訂正前 : 新漁網妨汚剤, 5-Tert-butyl-2′-methyl-4′nitrosalicylanilide (MK-76) のラット
訂正後 : 新漁網妨汚剤, 5-Tert-butyl-2'-methyl-4'nitrosalicylanilide (MK-76) のラット

訂正日: 2008/02/29 訂正理由: - 訂正箇所: 論文抄録訂正内容: Wrong : MK-76 (5-tert-butyl-2′-methyl-4′-nitrosalicylanilide) was given orally to Wistar rats in doses of 62.5, 125, 250, 500, 1000 and 2000mg/kg for 13 weeks.
Toxic symptoms observed in high-dose groups and caused by the administration of MK-76 were slight anemia, central necrosis in the hepatic lobule and some kidney damage. In addition, pneumonia and proliferation of the interlobular bile duct were observed but these were not effects of MK-76 administration.
No signs of toxicity were observed at doses of 500mg/kg or less.
Right : MK-76 (5-tert-butyl-2'-methyl-4'-nitrosalicylanilide) was given orally to Wistar rats in doses of 62.5, 125, 250, 500, 1000 and 2000mg/kg for 13 weeks.
Toxic symptoms observed in high-dose groups and caused by the administration of MK-76 were slight anemia, central necrosis in the hepatic lobule and some kidney damage. In addition, pneumonia and proliferation of the interlobular bile duct were observed but these were not effects of MK-76 administration.
No signs of toxicity were observed at doses of 500mg/kg or less.

訂正日: 2008/02/29 訂正理由: - 訂正箇所: PDFファイル訂正内容: -

抄録

MK-76 (5-tert-butyl-2'-methyl-4'-nitrosalicylanilide) was given orally to Wistar rats in doses of 62.5, 125, 250, 500, 1000 and 2000mg/kg for 13 weeks.
Toxic symptoms observed in high-dose groups and caused by the administration of MK-76 were slight anemia, central necrosis in the hepatic lobule and some kidney damage. In addition, pneumonia and proliferation of the interlobular bile duct were observed but these were not effects of MK-76 administration.
No signs of toxicity were observed at doses of 500mg/kg or less.

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訂正情報

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