Clinical Evaluation of ^99mTc-labeled Sodium Tripolyphosphate as a Bone Imaging Agent

Abstract

^99mTc complex of tripolyphosphate and stannous chloride has been evaluated as a bone seeking agent. This compound is prepared simply using “kit” method. Animal studies show that bone/muscle, bone/blood and bone/liver ratio are high enough to delineate the skeletal systems. This compound is promptly excreted in the urine. Various bone diseases are delineated by rectilinear scanning. A blood pool background is high at the end of two hours after injection. The optimal time for scanning is about three to six hours after injection. The image with ^99mTc-STPP is comparable to that with ^87mSr.